Pests and grapevine diseases in organic production are suppressed by preventive measures with a view to reducing the impact of the attack. Allowed substances acting on patogenous fungi, insects, mites and other harmful organisms are used, if appropriate. Insecticides of plant origin are used in the organic production of grapevine, as well as vegetable oils, powders and insecticidal soaps that are selective, with a narrow range of effects and of lower toxicity, as well as biological products. As a rule, such plant protection products require a more frequent application. Copper-based and sulphur-based fungicides are still leading products in suppressing grapevine diseases. Researches are directed to decrease the quantity of application and to find their replacement by also efficient fungicides. A special emphasis is put on researching the efficient fungicides for suppressing Botrytis bunch rot and factors causing grapevine wood diseases (Esca and Eutypa) in organic production. Along with copper and sulphur, different substances such as bicarbonates, plant extracts and oils, biological products being parasites, patogenous or diseases agent antagonists, and natural products such as milk and whey are applied in the organic production of grapevine.