This study analyzes the socio-economic factors that influence people’s decision to become fishermen in the central region of Ghana. Using a well structured interview schedule, a random sample of 98 people from Elmina in the central region of Ghana was selected for the study. Results from the descriptive statistics analysis of respondents identified fishing as a family business, minimum skills requirement and ready market for fish demand as factors that motivated majority of the people into fishing. Lack of storage facilities, access to credit, lack of government assistance and unpredictable changes in weather conditions on sea were the main constraints to fishing activities. Results from the logistic regression model indicated that household size and access to credit were significant factors that positively influenced people’s decision to become fishermen. The regression analysis further revealed that engaging in other income generating activity and being educated significantly reduces the probability to start fishing business.