Field experiments were conducted at the Teaching and Research Farm of the Federal University of Agriculture, Abeokuta (7^o 20’N, 3⁰ 23’E) during the 2014 early and late cropping seasons to evaluate the effect of weeding frequency and phosphorus fertilizer application on the growth and grain yield of the early maturing cowpea variety (Vigna unguiculata L. Walp). The experiment was laid out in a split-plot arrangement fitted into a Randomized Complete Block Design with three replications. The main plot consisted of three phosphorus fertilizer rates (0, 15 and 30 P₂O₅kg ha^-1) while the subplot comprised five weeding frequencies (no weeding, weed-free, hoe weeding at 3 weeks after sowing (WAS), hoe weeding at 3 and 6 WAS and weeding at 3, 6 and 9 WAS). The results showed that plots treated with phosphorus fertilizer at 15 kg ha^-1 produced the highest number of leaves and the tallest plant in the late season while the highest grain yield was recorded in the early trials. Weeding at 3, 6 and 9 WAS during the early season trial gave the highest grain yield compared with other weeding treatments. Unchecked weed infestation reduced yield by 53.10 % and 49.9 % in the early and late seasons respectively compared to the maximum obtained from weed-free plots. This study concluded that application of 15 kg P₂O₅ ha^-1 and weed removal at 3, 6 and 9 WAS were effective for effective weed control and optimum grain yield in cowpea production.