The preliminary results of a two-year comparative investigation of two genotypes of ribwort-plantain in the agroecological conditions of west Serbia (Gorobilje), south Banat (Pančevo) are given. Genotype originating from the international exchange (marked with 'D') was compared with 'domestic' genotype which has been raised at the Medicinal Plants Research Institute 'Dr Josif Pančić', Belgrade, for more than ten years.